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Evaluation of the effect of Pomegranate peel ointment in episiotomy

Evaluation of the effect of Pomegranate (Punica granatum) peel extract ointment on pain severity and episiotomy wound healing: a randomized clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20260423069137N1
Enrollment
120
Registered
2026-05-09
Start date
2026-05-21
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Episiotomy. Perineal laceration during delivery

Interventions

Intervention 1: Intervention group1: Recipients of pomegranate peel extract ointment. In this study, pomegranate peel was obtained from the herbal market (herbalist shop), and after identity confirmat

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Gestational age between 37 and 42 completed weeks Maternal age between 18 and 35 years Body mass index (BMI) within the range of 18.6 to 30 Iranian nationality Resident of Kermanshah Province Ability to read and write Singleton pregnancy with cephalic presentation Neonatal birth weight between 2,500 and 4,000 grams Vaginal delivery with mediolateral episiotomy, without perineal tear and without the use of assisted delivery tools (forceps or vacuum)

Exclusion criteria

Exclusion criteria: Prolonged rupture of membranes lasting more than 24 hours Severe anemia during pregnancy (hemoglobin level below 7) Consumer of cigarettes, alcohol, and drugs Presence of any underlying condition that impairs wound healing (including chronic systemic diseases, cardiopulmonary disorders, connective tissue diseases, anemia, diabetes, malnutrition, hemophilia, psychiatric disorders, and renal failure), as well as obstetric complications such as gestational diabetes, preeclampsia, eclampsia, coagulation disorders, placental abruption, chorioamnionitis, and immune system deficiencies, based on the individual’s statement and medical/midwifery records Use of any medications that may affect wound healing, such as corticosteroids, anticoagulants, antiepileptic drugs, immunosuppressants, broad-spectrum antibiotics, and chemotherapeutic agents Labor dystocia and prolongation of the stages of labor History of hypersensitivity to topical or herbal medications, as reported by the individual

Design outcomes

Primary

MeasureTime frame
Pain intensity score on the Visual Analog Scale for pain. Timepoint: Before intervention (2 hours postpartum) and on the first, fifth, and tenth days postpartum. Method of measurement: Visual Analog Scale.;Wound healing score on the Redness, Edema, Echymosis, Discharge, Approximation scale. Timepoint: Before intervention (2 hours postpartum) and on the first, fifth, and tenth days postpartum. Method of measurement: Redness, Edema, Echymosis, Discharge, Approximation scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSahar Nazarabadi

Shahid Beheshti University of Medical Sciences

sahar.nazarabadi@sbmu.ac.ir+98 83 3424 5007

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026