Skip to content

Effect of Photobiomodulation on Mental Functions in Obsessive-Compulsive Disorder

Investigating the effectiveness of Neurophotobiomodulation on executive functions and distress tolerance in patients with obsessive-compulsive disorder

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20260412069053N1
Enrollment
30
Registered
2026-05-03
Start date
2026-05-22
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obsessive-compulsive disorder. Obsessive-compulsive disorder

Interventions

Intervention 1: Intervention Group:The therapeutic intervention in the experimental group consisted of 10 sessions of transcranial photobiomodulation (tPBM) using the Fotino brain laser therapy device

Sponsors

Kerman University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 57 Years

Inclusion criteria

Inclusion criteria: Age between 18 and 65 years. Diagnosis of Obsessive-Compulsive Disorder (OCD) according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) by a specialist psychiatrist using the Structured Clinical Interview (SCID-5). No receipt of active pharmacological or psychotherapeutic treatment for at least 4 weeks prior to the study start, and no initiation of other treatments during the study period. A score between 16 and 25 on the Yale-Brown Obsessive Compulsive Scale (Y-BOCS) to confirm mild to moderate symptoms. Ability to understand the informed consent form and provide a signature.

Exclusion criteria

Exclusion criteria: History of active seizures or epilepsy (due to light sensitivity). Active skin diseases on the face or scalp that interfere with light exposure Pregnancy or breastfeeding (due to safety concerns regarding phototherapy)

Design outcomes

Primary

MeasureTime frame
Barclay Deficits in Executive Functioning Scale (BDEFS) score. Timepoint: Measurement at two time points: Pre-test (before the first intervention session) and Post-test (immediately after the 10th session). Method of measurement: Barclay Deficits in Executive Functioning Scale.;Distress Tolerance Scale (DTS) score. Timepoint: Measurement at two time points: Pre-test (before the first intervention session) and Post-test (immediately after the 10th session). Method of measurement: Distress Tolerance Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public Contactshima ferdosi

Kerman University of Medical Sciences

Shima.Ferdosi@ens.uk.ac.ir+98 34 3425 8039

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026