Comparison of the task-dependent effects of spatial, numerical, and verbal working memory

Comparison of the task-dependent effects of spatial, numerical, and verbal working memory under cerebellar transcranial direct current stimulation on prefrontal hemodynamic changes measured by functional near-infrared spectroscopy in healthy individuals

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20260411069044N1

Enrollment

Registered

2026-04-21

Start date

2026-04-21

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Working memory in healthy adults. Encounter for examination for normal comparison and control in clinical research program

Interventions

Intervention 1: Intervention group 1: Right cerebellar transcranial direct current stimulation (cDCS)In this group, cerebellar transcranial direct current stimulation (cDCS) is delivered at 2 mA for 2

Eligibility

Sex/Gender

Male

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Age above 18 years ; no use of medications affecting brain activity Right-handedness Normal vision and hearing No history of neurological or psychiatric disorders. no use of medications affecting brain activity

Exclusion criteria

Exclusion criteria: Emergence of neurological or psychiatric symptoms Lack of cooperation Use of medications or substances that affect brain activity Failure to comply with instructions

Design outcomes

Primary

Measure	Time frame
Hemodynamic activation patterns in the prefrontal cortex during different types of working memory tasks (spatial, numerical, and verbal), measured using fNIRS before and after stimulation. Timepoint: pre and post. Method of measurement: Computerized tasks and signal recording.	—

Secondary

Measure	Time frame
• Changes in verbal working memory scores before and after stimulation, assessed using the computerized Digit Span (backward) task. Timepoint: pre and post. Method of measurement: Computerized tasks and signal recording.;Changes in spatial working memory scores before and after stimulation, assessed using the computerized Corsi Block-Tapping test. Timepoint: pre and post. Method of measurement: Computerized tasks and signal recording.;• Changes in numerical working memory scores before and after stimulation, assessed using the computerized PASAT task. Timepoint: pre and post. Method of measurement: Computerized tasks and signal recording.	—

Measure

Time frame

• Changes in verbal working memory scores before and after stimulation, assessed using the computerized Digit Span (backward) task. Timepoint: pre and post. Method of measurement: Computerized tasks and signal recording.;Changes in spatial working memory scores before and after stimulation, assessed using the computerized Corsi Block-Tapping test. Timepoint: pre and post. Method of measurement: Computerized tasks and signal recording.;• Changes in numerical working memory scores before and after stimulation, assessed using the computerized PASAT task. Timepoint: pre and post. Method of measurement: Computerized tasks and signal recording.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed mohammad Saeid Sahaf

Mashhad University of Medical Sciences

sahhafms4022@mums.ac.ir+98 51 3846 2098

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026