Mental, behavioral, and neurodevelopmental disorders are conditions characterized by clinically significant disturbances in an individual’s cognition, emotional regulation, or behavior. These disorders reflect dysfunction in psychological, biological, or developmental processes, compromising mental and behavioral functioning. They are typically associated with distress or impairment in important areas of functioning, including personal, familial, social, educational, occupational, or other life
Conditions
Interventions
Intervention 1: Intervention group: In the intervention group, in addition to standard treatment measures, patients will use intranasal oxytocin spray (50 IU/mL) twice daily (one puff in each nostril
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
3 Years to 8 Years
Inclusion criteria
Inclusion criteria: Age between 3 and 8 years Diagnosis of Autism Spectrum Disorder Receiving standard treatment for at least 2 months prior to the start of the intervention No use of pituitary hormones, cortisol, androgens, or estrogens No cardiovascular or respiratory problems No comorbid psychiatric disorders
Exclusion criteria
Exclusion criteria: Occurrence of serious side-effects
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessment of patients’ status in terms of stereotyped behaviors, communication, social interaction, and developmental disorders. Timepoint: before and after the intervention. Method of measurement: Gilliam Autism Rating Scale (GARS).;Assessment of communication and social disorders, restricted and stereotyped interests, and motor and vocal tics. Timepoint: Before and after the intervention. Method of measurement: Autism Spectrum Screening Questionnaire (ASSQ). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAkram Boromand Dizji
Mashhad University of Medical Sciences
Outcome results
None listed