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Investigating the effect of using a comprehensive nurse-led program on the outcomes of weaning from mechanical ventilator in patients hospitalized in the special care units.

Investigating and comparing the effect of using a comprehensive nurse-led and physician-led program on the outcomes of weaning from mechanical ventilator in patients hospitalized in the special care units of the selected hospitals of Isfahan University of Medical Sciences

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20260307068970N1
Enrollment
35
Registered
2026-05-03
Start date
2026-03-09
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

weaning from mechanical ventilation in special care units patients..

Interventions

Intervention 1: Control group: In order to prevent the effectiveness error of the control group from the intervention group, at first the control group will enter the study and prepare for weaning fro

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients are include if they are 18 years old or more. Being mechanically ventilated for more than 48 hours. Intubation time less than 14 days. Lack of chronic cardiovascular, COPD, ARDS, central and peripheral nervous system degenerative diseases base as well as ICU patient charts and diagnosis of expert physician.

Exclusion criteria

Exclusion criteria: Patients or patients’ families unwillingness to participate in the study. The patient is already prepare for weaning. Missing the patient during the study. Occurrence brain death during the study. Transferring the patient to other health care center during the study. Sudden extubated without planning. Serious complications such as respiratory arrest, shock and hemodynamic instability that requires urgent intervention.

Design outcomes

Primary

MeasureTime frame
In the study of "investigating the effect of using a comprehensive nurse-led program on the outcomes of weaning from mechanical ventilator in patients hospitalized in the special care units" the early outcome is "the frequency of reintubation in the control and the intervention group 48 hours after intervention". Timepoint: The time of measuring of re-intubation is "from the beginning of weaning until 48 hours later". Method of measurement: The way of measuring is " questionnaire" which is answered with Yes or No. This questionnaire was designed by the researcher after conducting an expert panel and incorporating the opinions of relevant professors and physicians.;In the study of "investigating the effect of using a comprehensive nurse-led program on the outcomes of weaning from mechanical ventilator in patients hospitalized in the special care units" the other outcome is "arterial oxygen saturation level in control and intervention group before the intervention and every 15 minute till 2 hours after the intervention". Timepoint: The time of measuring of arterial oxygen saturation level is "before the intervention and every 15 minute till 2 hours after the intervention". Method of measurement: The way of measuring is "the checklist of assessment of respiratory indicators" which is expressed with percentage.;In the study of "investigating the effect of using a comprehensive nurse-led program on the outcomes of weaning from mechanical ventilator in patients hospitalized in the special care units" the other outcome is "respiratory rate in control and intervention group before the intervention and every 15 minute till 2 hours after the intervention". Timepoint: The time of measuring of respiratory rate is "before the intervention and every 15 minute till 2 hours after the intervention". Method of measurement: The way of measuring is "the checklist of assessment of respiratory indicators" which is expressed with numbers.;In the study of "investigating the effect of using

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNiloofar Fadaei

Esfahan University of Medical Sciences

niloo.fdy@gmail.com+98 31 3668 0048

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026