Blood pressure in patients with cerebral hemorrhage.
Conditions
Interventions
Intervention 1: In intervention group , the starting dose of sacubitril-valsartan will be 24/26 (50) mg twice daily and will be gradually increased to 100 to 200 mg twice daily (depending on patient t
Sponsors
Kermanshah University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: ICH patients with stage 2 or higher hypertension and admitted to the ICU Do not have contraindications for taking sacubitril-valsartan or enalapril Have tolerated previous treatment with ARB and ACEi
Exclusion criteria
Exclusion criteria: Renal failure Liver failure Have a history of receiving ACEi within the last 36 hours prior to hospitalization If a patient develops renal failure during the study, the patient will be withdrawn and followed up. The minimum study period (minimum study time) will be 10 days, and patients who have been treated with the two drugs mentioned for less than 10 days will be excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Systolic and diastolic blood pressure. Timepoint: The minimum review time will be 10 days. Method of measurement: Systolic and diastolic blood pressure will be recorded every 12 hours with a mercury sphygmomanometer by the ICU technician. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMalektaj Siabani
Kermanshah University of Medical Sciences
Outcome results
None listed