Amphetamine toxicity. Poisoning by, adverse effect of and underdosing of amphetamines
Conditions
Interventions
Intervention 1: Intervention group: First, three doses of midazolam at a dose of 0.3 mg/kg per dose, followed by a midazolam drip at a dose of 1 microgram/kg per minute, will be given and continued un
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Months to 14 Years
Inclusion criteria
Inclusion criteria: Patient from 1 month to 14 years old Definite diagnosis of amphetamine toxicity with positive urine toxicology test
Exclusion criteria
Exclusion criteria: The history of allergy to clonidine or Midazolam Shock or respiratory distress with need of intubation Children with metabolic syndrome or having interfering drugs such as Pseudoephedrine Any kind of disease , including heart disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The mean difference in COMFORT - b scale scores between the two groups. Timepoint: baseline ( before intervention ) . 30 minutes after the first dose . then every four hours to 24 hours. Method of measurement: COMFORT - b scale scores. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNafise Purbadakhshan
Mashhad University of Medical Sciences
Outcome results
None listed