Comparison of the effect of sequence in concurrent training on inflammatory markers in obesity

Comparison of the effect of sequence in concurrent resistance-aerobic training and aerobic-resistance on neutrophil to lymphocyte ratio, platelet to lymphocyte ratio, systemic immune inflammation index and insulin resistance in obese women

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20260210068828N1

Enrollment

Registered

2026-05-19

Start date

2026-05-22

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity.

Interventions

Intervention 1: Intervention group: Concurrent aerobic-resistance training. In this group, subjects first perform aerobic training and then resistance training. Intervention 2: Intervention group: Con

Eligibility

Sex/Gender

Female

Age

30 Years to 45 Years

Inclusion criteria

Inclusion criteria: Age range between 30 and 45 years Obesity (BMI = 30 kg/m2) No active or chronic infectious or inflammatory diseases No history of unstable weight (weight change of more than three kilograms in three months before selecting the sample for this study) No smoking No special diet Low physical activity, and no participation in regular physical activities.

Exclusion criteria

Exclusion criteria: Absence of more than two consecutive sessions and three non-consecutive sessions Participation in other regular physical activities other than the studied exercise program Suffering from any chronic disease (diabetes, cardiovascular diseases, etc.) or acute disease during the study.

Design outcomes

Primary

Measure	Time frame
Neutrophil to lymphocyte ratio. Timepoint: Before the start of the intervention and 12 weeks afterwards. Method of measurement: With an automated blood cell counter XP-100 (Sysmex, Kobe, Japan).;Platelet to lymphocyte ratio. Timepoint: Before the start of the intervention and 12 weeks afterwards. Method of measurement: With an automated blood cell counter XP-100 (Sysmex, Kobe, Japan).;Systemic immune inflammation index. Timepoint: Before the start of the intervention and 12 weeks afterwards. Method of measurement: Neutrophil count X Platelet count/Lymphocyte count.;Insulin resistance. Timepoint: Before the start of the intervention and 12 weeks afterwards. Method of measurement: HOMA-IR=Fasting glucose x fasting insulin/405.	—

Measure

Time frame

Neutrophil to lymphocyte ratio. Timepoint: Before the start of the intervention and 12 weeks afterwards. Method of measurement: With an automated blood cell counter XP-100 (Sysmex, Kobe, Japan).;Platelet to lymphocyte ratio. Timepoint: Before the start of the intervention and 12 weeks afterwards. Method of measurement: With an automated blood cell counter XP-100 (Sysmex, Kobe, Japan).;Systemic immune inflammation index. Timepoint: Before the start of the intervention and 12 weeks afterwards. Method of measurement: Neutrophil count X Platelet count/Lymphocyte count.;Insulin resistance. Timepoint: Before the start of the intervention and 12 weeks afterwards. Method of measurement: HOMA-IR=Fasting glucose x fasting insulin/405.

—

Secondary

Measure	Time frame
Body composition. Timepoint: Before the intervention and 12 weeks after it. Method of measurement: Body composition analyzer.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSoheyla Alamdar

The University of Birjand

soheyla.alm70@gmail.com+98 51 4261 4196

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026