Condition 1: Infertility. Condition 2: Adenomyosis. Female infertility Adenomyosis of the uterus
Conditions
Interventions
Intervention group: Cabergoline 0.5mg twice weekly for 3 months + GnRH agonist protocol.
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
30 Years to 42 Years
Inclusion criteria
Inclusion criteria: Trying to conceive for more than 6 months without success Age: 30-42 years. Diagnosis of adenomyosis on ultrasound. Regular menstrual cycles of 24-35 days. Body Mass Index (BMI) between 19 and 30 (19 < BMI < 30). Having two Grade A oocytes by age 40 and three Grade A oocytes between the ages of 41-42.
Exclusion criteria
Exclusion criteria: Use of infertility treatments in the last 6 months. Previous history of 2 failed embryo transfers. Pelvic pathologies other than uterine adenomyosis. Previous history of hypersensitivity to cabergoline.Intolerance to cabergoline side effects during the study. Failure of ovulation induction and transfer to the uterus during the study. Severe spermatogenesis disorder (azoospermia) in the patient's partner.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Implantation Rate. Timepoint: 1 week after positive test of Bhcg. Method of measurement: Sonography.;Biochemical Rate. Timepoint: Two weeks after embryo transfer. Method of measurement: Serum Level of Bhcg.;Clinical Pregnancy Rate. Timepoint: 2 weeks after positive test of Bhcg. Method of measurement: Sonography.;Miscarriage Rate. Timepoint: Early 20 weeks of pregnancy. Method of measurement: Taking patient medical history and Sonography. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactLida Shafieyan
Tehran University of Medical Sciences
Outcome results
None listed