Designing a diagnostic test for Helicobacter pylori infection through exhalation

Designing a new diagnostic method for Helicobacter pylori infection based on exhaled ammonium levels and comparing it with other common diagnostic methods.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20260209068803N1

Enrollment

142

Registered

2026-05-25

Start date

2026-02-19

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Helicobacter pylori infection. Helicobacter pylori [H. pylori] as the cause of diseases classified elsewhere

Interventions

Intervention group: Consuming a dry food item before the breath test (for example, a biscuit).

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All patients with gastrointestinal symptoms of Helicobacter pylori infection are referred to gastroenterologist for endoscopy.

Exclusion criteria

Exclusion criteria: People with kidney, liver and tuberculosis diseases

Design outcomes

Primary

Measure	Time frame
The amount of exhaled ammonium. Timepoint: up to 30 minutes after eating. Method of measurement: Collecting the patient's exhalation in a special tube, adding solutions and reagents and measuring the exhaled ammonium concentration with a photometer.	—

Secondary

Measure	Time frame
Positive or negative test result indicating Helicobacter pylori infection or not. Timepoint: 15 minutes after sampling. Method of measurement: Using a photometer.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmin Esmaeili

Esfahan University of Medical Sciences

amin_mahoor@yahoo.com+98 31 3621 4267

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026