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intraperitoneal ondansetron in bariatric surgery

Comparative evaluation of abdominal pain intensity after bariatric surgery following intraperitoneal injection of ondansetron versus placebo.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20260205068769N1
Enrollment
80
Registered
2026-05-11
Start date
2026-03-06
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain from bariatric surgery in obese patient. Overweight and obesity

Interventions

Intervention 1: Intervention group:15 minutes after the end of surgery in the recovery room, one group will be injected with a vial of intraperitoneal ondansetron (4 mg, made up to 10 cc with distille

Sponsors

Karaj University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: BMI more than 40

Exclusion criteria

Exclusion criteria: Patients who require frequent use of analgesics due to an underlying disease such as osteoarthritis. Patients with drug addiction to opioids. Patients with contraindications to ondasteron injection.

Design outcomes

Primary

MeasureTime frame
Abdominal pain severity after bariatric surgery following intraperitoneal injection of ondansetron and placebo. Timepoint: A daily chart is used to assess primary outcomes, including pain intensity, and pain intensity is valid and reliable every 6 hours for 4 consecutive days, and its reliability will be measured in Visual Analogue Scale .It should be noted that the scoring method on the pain chart, from 0 to 10, will be explained to the patients before each question. In case of grade 4 pain, Apotel is prescribed, and in case of grade 6 pain, pethidine is prescribed. Method of measurement: Visual Analogue Scale pain chart.

Secondary

MeasureTime frame
Hospital stay time. Timepoint: At the time of discharge. Method of measurement: Referral to the patient file.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBabak Mansourian

Karaj University of Medical Sciences

b.mansourian@yahoo.com+98 21 4410 3677

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026