The effect of probiotics on obsessive-compulsive disorder

Evaluation of the effect of probiotic supplementation on sexual function in women with Obsessive-Disorder: A randomized clinical trial study

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20260205068763N1

Enrollment

126

Registered

2026-02-15

Start date

2026-03-16

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obsessive-compulsive disorder. Obsessive-compulsive disorder

Interventions

Intervention 1: Intervention group: Taking anti-anxiety medication as prescribed by a doctor along with Lactofem capsules (containing Lactobacillus acidophilus 109×2, Bifidobacterium bifidus 109×2, La

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Diagnosis of obsessive-compulsive disorder based on DSM-5 by a psychiatrist or clinical psychologist A Y-BOCS total score of = 16 indicates moderate to severe severity of obsessions.

Exclusion criteria

Exclusion criteria: Having other psychiatric disorders affecting sexual function, such as depression

Design outcomes

Primary

Measure	Time frame
Sexual function. Timepoint: Before and immediately after the intervention. Method of measurement: Using the Female Sexual Function Index (FSFI).;The intensity of the obsession. Timepoint: Before and immediately after the intervention. Method of measurement: Using the Yale-Brown Obsessive Compulsive Scale (Y-BOCS).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Bazargani-pour

Yasouj University of Medical Sciences

f.bazarganipour@gmail.com+98 74 3323 5153

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026