Evaluation of the Effect of Topical Minoxidil on Nail Growth.
Conditions
Interventions
Intervention 1: Intervention group: Definition of Intervention Method and Exact Dosage :Intervention: Application of topical minoxidil in the form of gel or solution on the nails .Duration: The durati
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Age above 18 years Willingness to participate in the study and sign an informed consent form No history or sensitivity or allergic reactions to minoxidil General good health and absence of serious systemic diseases (such as uncontrolled diabetes or autoimmune diseases) No active infections or fungal nail diseases. No use of other medications that may affect nail growth (such as terbinafine or biotin supplements ) in the past three months. Healthy nails or mild dystrophic nail problems that do not require severe medical severe medical interventions.
Exclusion criteria
Exclusion criteria: History of hypersensitivity or allergic reaction to minoxidil Presence of an active nail infection, including fungal infections Unhealthy nails with severe dystrophic changes requiring intensive pharmacological intervention Use of medications that may affect nail growth (such as terbinafine or biotin supplements) within the past three months Presence of serious systemic diseases (such as uncontrolled diabetes or autoimmune disorders)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in the rate of nail growth, which can be assessed by measuring nail length at baseline and at the end of the intervention period. Timepoint: The duration of minoxidil use is typically 8 to 12 weeks. In addition, researchers will assess nail status every two weeks and record data based on nail length, thickness, and overall nail health. Method of measurement: Specifications of Data Collection Instruments and Methods of Data Collection:Demographic and Clinical Data Collection Form:A structured form will be designed to record the following information for each participant:Name, age, sex, and general health status.History of nail disorders (such as nail dystrophy or onychomadesis).Use of medications or supplements affecting nail health (such as biotin or zinc supplements).Possible adverse effects associated with the use of minoxidil.Precision Millimeter Ruler or Digital Measurement Tools:To measure the rate of nail growth over a defined time period (e.g., monthly), the following tools will be used:High-precision millimeter ruler.Mobile applications or digital devices capable of measuring and recording nail length.Self-Assessment Questionnaire for Adverse Effects:Participants will complete a questionnaire every two weeks to report any potential side effects, such as skin irritation, redness, or inflammation.Researcher Assessment Checklist:At each follow-up visit, researchers will evaluate nail changes based on the following criteria:Nail length (measured in millimeters).Nail appearance (smooth or with fissures/cracks).Nail thickness (if feasible). | — |
Secondary
| Measure | Time frame |
|---|---|
| Nail thickness. Timepoint: Additionally, the researchers will evaluate the nail condition at two-week intervals and document data based on nail length, nail thickness, and overall nail health. Participants will be regularly followed up throughout the 8-week study period. Method of measurement: A precise millimeter ruler or a digital measuring device.;Nail quality (structural and appearance characteristics). Timepoint: Additionally, the researchers will evaluate the nail condition at two-week intervals and document data based on nail length, nail thickness, and overall nail health. Participants will be regularly followed up throughout the 8-week study period. Method of measurement: By visual inspection of the nail appearance (smooth or with cracks).;.Presence or absence of side effects during the treatment period. Timepoint: Additionally, the researchers will evaluate the nail condition at two-week intervals and document data based on nail length, nail thickness, and overall nail health. Participants will be regularly followed up throughout the 8-week study period. Method of measurement: Self-Assessment Side Effects Questionnaire : Participants will complete a questionnaire every two weeks to report any potential side effects (such as skin irritation, redness, or inflammation). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFateme Sabery
Tehran University of Medical Sciences
Outcome results
None listed