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Effect of saffron extract on neurological recovery and reducing disability in patients with ischemic stroke

Efficacy of Saffron extract on neurological disability based on Modified Rankin Scale in patients with mild to moderate acute ischemic stroke

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20260127068678N1
Enrollment
74
Registered
2026-01-30
Start date
2025-10-29
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic Stroke. Cerebellar stroke syndrome

Interventions

Intervention 1: Intervention group: Intervention group: Including 37 patients who will receive 30 mg of saffron capsules from Duralife -Faran Chemi Pharmaceutical Company (15 mg twice a day) for 30 da

Sponsors

Ghoum University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients with a definitive diagnosis of acute ischemic stroke Age between 18 and 80 years Glasgow Coma Scale (GCS) score of 15 National Institutes of Health Stroke Scale (NIHSS) score less than 15 Absence of coagulation or platelet disorders at admission Obtaining informed consent from the patient or their legal guardian

Exclusion criteria

Exclusion criteria: History of previous stroke or cognitive disorders and Alzheimer's disease Receiving thrombolytic therapy (rtPA) for the current stroke Known hypersensitivity to saffron Suffering from advanced liver or kidney diseases Occurrence of fever or seizures at the time of initial admission

Design outcomes

Primary

MeasureTime frame
Level of consciousness. Timepoint: arrival; hospitalization time; while receiving medication. Method of measurement: Glasgow coma scale.

Secondary

MeasureTime frame
Length of hospitalization. Timepoint: The time of the patient's discharge from the hospital. Method of measurement: National Institutes Of Health Stroke Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Mohammadi

Ghoum University of Medical Sciences

mohammady.zahra1367@gmail.com+98 25 3345 2123

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026