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The Effect of Aromatherapy on Pain and Hemodynamic Indices

Comparing the effect of aromatherapy with rosemary and Mentha piperita essential oils on pain and hemodynamic indicators in patients after laparoscopic cholecystectomy

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20260125068662N1
Enrollment
93
Registered
2026-02-16
Start date
2026-02-09
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cholecystectomy. Acquired absence of other parts of digestive tract

Interventions

Intervention 1: Intervention group 1: 3 drops of 100% Peppermint essential oil (for the mint group), prepared from the Giyah Kala company, are dropped onto a sterile cotton ball. This is attached to t

Sponsors

Khomein University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients eligible for elective cholecystectomy surgery are adults (above 18 years of age) who have at least basic literacy (able to read and write) They must have no impairment of smell, speech, hearing, or vision no known allergy to peppermint or rosemary based on the initial patient interview and medical records Patients should have no history of pulmonary or respiratory diseases no substance abuse no use of anticoagulant medications no history of hypertension, and no psychiatric disorders. In addition, they should have no history of epilepsy or chronic headaches not be pregnant The postoperative pain intensity should be three or greater on the Visual Analogue Scale (Visual Analog Scale) Before starting the intervention, the effects of anesthesia must have completely worn off, and the patient should be fully conscious after the operation not connected to a ventilator, not receiving oxygen therapy, and able to breathe spontaneously

Exclusion criteria

Exclusion criteria: Use of analgesic or narcotic medications for pain relief beyond the routine postoperative orders. Presence of physical complications or instability in hemodynamic and physiological status, such as occurrence of cardiac arrhythmia, respiratory problems, abnormal bleeding blood pressure instability (including unusual increase or decrease during surgery or immediately after surgery in the recovery room), as well as any other abnormal condition reported by operating room staff or documented in the patient’s file.

Design outcomes

Primary

MeasureTime frame
Postoperative pain intensity based on Visual Analog Scale. Timepoint: before the intervention (aromatherapy) and at 5, 15, 30, and 60 minutes after aromatherapy. Method of measurement: visual Analog Scale (VAS) will be used to determine the presence and severity of pain.;Heart rate. Timepoint: Heart rate monitoring will be performed before the intervention (aromatherapy) and at 5, 15, 30, and 60 minutes after aromatherapy. Method of measurement: A portable monitor is used to measure heart rate.;Systolic blood pressure. Timepoint: Blood pressure control will be performed before the intervention (aromatherapy) and at 5, 15, 30, and 60 minutes after aromatherapy. Method of measurement: Using a blood pressure monitor, portable monitor.;Respiratory rate. Timepoint: Breathing rate will be monitored before the intervention (aromatherapy) and at 5, 15, 30, and 60 minutes after aromatherapy. Method of measurement: The number of breaths was also counted for one minute by the researcher using a stopwatch.;Diastolic blood pressure. Timepoint: Blood pressure control will be performed before the intervention (aromatherapy) and at 5, 15, 30, and 60 minutes after aromatherapy. Method of measurement: Using a blood pressure monitor, portable monitor.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Salehi

Khomein University of Medical Sciences

fatemeh.salehi1551@gmail.com+98 86 3280 0813

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026