"Effect of Soda Rosmarinus extract on knee osteoarthritis"

"Investigating the local effect of Soda Rosmarinus extract on Knee Osteoarthritis outcomes"

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20260123068643N1

Enrollment

Registered

2026-02-11

Start date

2026-02-09

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoarthritis. Osteoarthritis of knee

Interventions

Intervention 1: Intervention group: Eligible patients assigned to this group through block randomization will apply 9.4% Oshnan ointment twice daily to the knee for eight weeks. Intervention 2: Contro

Eligibility

Sex/Gender

All

Age

50 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients over 50 years of age, of both sexes, diagnosed with chronic knee osteoarthritis by an orthopedic specialist according to the ACR guidelines. Patients who give informed consent and are willing to cooperate in the research. Ability to answer the questionnaire.

Exclusion criteria

Exclusion criteria: Acute or septic arthritis. History of knee surgery. Significant cognitive impairment.

Design outcomes

Primary

Measure	Time frame
Knee pain score from the Knee Injury and Osteoarthritis Outcome Score questionnaire. Timepoint: Immediately before the start of the intervention, 8 and 12 weeks after the start of the intervention. Method of measurement: Knee Injury and Osteoarthritis Outcome Score questionnaire.;Joint symptom score (stiffness, locking, and swelling) from the Knee Injury and Osteoarthritis Outcome Score questionnaire. Timepoint: Immediately before the start of the intervention, 8 and 12 weeks after the start of the intervention. Method of measurement: Knee Injury and Osteoarthritis Outcome Score questionnaire.;Performance score in daily activities from the Knee Injury and Osteoarthritis Outcome Score questionnaire. Timepoint: Immediately before the start of the intervention, 8 and 12 weeks after the start of the intervention. Method of measurement: Knee Injury and Osteoarthritis Outcome Score questionnaire.;Recreation and sports performance score from the Knee Injury and Osteoarthritis Outcome Score questionnaire. Timepoint: Immediately before the start of the intervention, 8 and 12 weeks after the start of the intervention. Method of measurement: Knee Injury and Osteoarthritis Outcome Score questionnaire.	—

Measure

Time frame

Knee pain score from the Knee Injury and Osteoarthritis Outcome Score questionnaire. Timepoint: Immediately before the start of the intervention, 8 and 12 weeks after the start of the intervention. Method of measurement: Knee Injury and Osteoarthritis Outcome Score questionnaire.;Joint symptom score (stiffness, locking, and swelling) from the Knee Injury and Osteoarthritis Outcome Score questionnaire. Timepoint: Immediately before the start of the intervention, 8 and 12 weeks after the start of the intervention. Method of measurement: Knee Injury and Osteoarthritis Outcome Score questionnaire.;Performance score in daily activities from the Knee Injury and Osteoarthritis Outcome Score questionnaire. Timepoint: Immediately before the start of the intervention, 8 and 12 weeks after the start of the intervention. Method of measurement: Knee Injury and Osteoarthritis Outcome Score questionnaire.;Recreation and sports performance score from the Knee Injury and Osteoarthritis Outcome Score questionnaire. Timepoint: Immediately before the start of the intervention, 8 and 12 weeks after the start of the intervention. Method of measurement: Knee Injury and Osteoarthritis Outcome Score questionnaire.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Salamehzadeh zavareh

Kashan University of Medical Sciences

salamehzadeh-f@kaums.ac.ir+98 910 079 3899

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026