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anesthesia in root canal retreatment

A comparison between anesthetic efficacy of articaine and lidocaine secondary endodontic treatment in mandibular molar teeth : A randomized clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20260122068639N1
Enrollment
60
Registered
2026-02-16
Start date
2026-02-14
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Root canal retreatment of mandibular molars. Other and unspecified diseases of pulp and periapical tissues

Interventions

Intervention 1: Intervention group: Use of supplementary infiltration injection of Articaine after mandibular block injection with Lidocaine in root canal retreatment of manibular molars. Intervention

Sponsors

Kerman University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: – First or second mandibular molars with a history of root canal treatment having a Periapical Index (PAI) score of 1, 2, or 3. Teeth previously treated with root canal therapy but unsuccessful and having developed apical periodontitis (AP). Individuals with a spontaneous pain score of less than 54 mm on the HP-VAS scale Teeth with radiographically poor-quality root canal fillings. Teeth with failed or insufficient coronal restoration requiring root canal retreatment. Patients aged 18 to 65 years Patients with ASA I and ASA II Patients without acute pain or extracoral swelling Patients with acute apical abscess Patients who voluntarily participate in the study and are available for follow-up Absence of severe periodontal problem in the tooth in question Teeth with prefabricated posts

Exclusion criteria

Exclusion criteria: Individuals with a spontaneous pain score greater than 54 on the HP-VAS scale Patients whose retreatment requires two sessions.– Teeth with internal or external root resorption Teeth with vertical root fracture or dental crack Teeth with open or immature apex Patients with systemic diseases (such as bone metabolism disorders) Patients taking medications affecting bone metabolism Patients with acute pain who have taken analgesics in the past 24 hours Patients who did not attend follow-up sessions third molars Presence of severe periodontal disease rendering the tooth unsuitable for endodontic treatment Periodontal probing depth greater than 3 mm. Root canal treatment extending beyond the canal length and over instrumentation Teeth with cast posts or broken files inside the canal Patients with contraindications to NSAIDs Patients who experience treatment errors during retreatment Patients who are accidentally over-instrumented during the procedure Patients in whom post-operative radiography shows any extrusion of the root canal filling material Teeth with extensive caries making restoration impossible

Design outcomes

Primary

MeasureTime frame
Pain score in the Heft-Parker Visual Analog Scale (HP-VAS) questionnaire. Timepoint: Before the start of treatmentDuring the injectionDuring removal of the coronal restorationDuring removal of gutta-percha from the canalsDuring canal preparation and irrigationDuring obturationImmediately after completion of the procedure,6 hours after the procedure,12 hours after the procedure, 24 hours after the procedure, 2 days after the procedure, 3 days after the procedure?7 days after the procedure. Method of measurement: Heft-Parker Visual Analog Scale (HP-VAS) questionnaire.

Secondary

MeasureTime frame
Quality of life score. Timepoint: Before the start of treatment, 7 days after treatment. Method of measurement: Oral Health Impact Profile-14 (OHIP-14) questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamed Manouchehrifar

Kerman University of Medical Sciences

hamed_man61@yahoo.com+98 914 315 4323

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026