Postoperative bleeding.
Conditions
Interventions
Intervention group: Application of amniotic membrane allograft at the surgical site according to protocol.
Sponsors
Hamedan University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
25 Years to 55 Years
Inclusion criteria
Inclusion criteria: Women aged 25 to 55 years Diagnosis of cervical intraepithelial neoplasia grade 2 or 3 Candidate for Loop Electrosurgical Excision Procedure conization Normal coagulation profile including PT and PTT Normal hemoglobin level Ability to provide written informed consent
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemostasis level after cervical conization. Timepoint: During surgery and at 3, 6, and 24 hours after conization. Method of measurement: Menstrual pictogram (recording the amount of bleeding with each replacement of medium sanitary pad.;Pain level after cervical conization. Timepoint: 3, 6, and 24 hours after surgery. Method of measurement: Visual Analogue Scale for pain.;Cervical stenosis after conization. Timepoint: First menstrual cycle after surgery and three-month follow-up with colposcopy. Method of measurement: Colposcopy by gynecologic oncologist and menstrual pictogram completed by patient.;Recurrence of cervical intraepithelial neoplasia. Timepoint: 3, 6, and 12 months after surgery by colposcopy and pathology evaluation. Method of measurement: Colposcopy by the same gynecologic oncologist and pathology evaluation by the same pathologist. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSima Kamkari
Hamedan University of Medical Sciences
Outcome results
None listed