The effectiveness of transcranial direct current stimulation in individuals with rumination

The effectiveness of transcranial direct current stimulation on executive functions in individuals with elevated rumination

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20260119068613N1

Enrollment

Registered

2026-01-22

Start date

2026-02-19

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

High rumination.

Interventions

Intervention 1: Intervention group: The group receiving transcranial direct current stimulation (tDCS) will have the anode electrode placed over the left dorsolateral prefrontal cortex (DLPFC) and the

however, the stimulation procedure will differ. In both the experimental and placebo studies, stimulation is ramped up to 1.5 milliamperes. The key difference lies in the duration of the stimulation:

Eligibility

Sex/Gender

All

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Being between 18 and 35 years of age and providing informed consent to participate in the study Obtaining a score of 64 or higher on the Penn State Worry Questionnaire (PSWQ) Obtaining a score of 50 or higher on the Ruminative Responses Scale (RRS) Obtaining a score below 23 on the Patient Health Questionnaire (PHQ) and the absence of suicidal ideation indicative of major depressive disorder, as determined by responses to Item 9 of the Patient Health Questionnaire

Exclusion criteria

Exclusion criteria: Presence of neuropsychological or neurological disorders, including brain diseases such as epilepsy Concurrent receipt of psychological interventions Use of psychiatric medications? Substance abuse or dependence

Design outcomes

Primary

Measure	Time frame
Working memory. Timepoint: Pre - intervention, post - intervention, one month after the intervention. Method of measurement: N - back software.;Inhibitory control. Timepoint: Pre - intervention, post - intervention, one month after the intervention. Method of measurement: Go no go software.;Cognitive flexibility. Timepoint: Pre - intervention, post - intervention, one month after the intervention. Method of measurement: Wisconsin card sorting test software.;Depressive rumination scores obtained on the Ruminative Responses Scale (RRS). Timepoint: Pre - intervention, post - intervention, one month after the intervention. Method of measurement: Scores on the Depressive Rumination subscale of the Ruminative Responses Scale (RRS).	—

Measure

Time frame

Working memory. Timepoint: Pre - intervention, post - intervention, one month after the intervention. Method of measurement: N - back software.;Inhibitory control. Timepoint: Pre - intervention, post - intervention, one month after the intervention. Method of measurement: Go no go software.;Cognitive flexibility. Timepoint: Pre - intervention, post - intervention, one month after the intervention. Method of measurement: Wisconsin card sorting test software.;Depressive rumination scores obtained on the Ruminative Responses Scale (RRS). Timepoint: Pre - intervention, post - intervention, one month after the intervention. Method of measurement: Scores on the Depressive Rumination subscale of the Ruminative Responses Scale (RRS).

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmin Nasiri

The University of Kurdistan

aminnasiri641@gmail.com+98 51 3614 9423

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026