Sarcopenia. Sarcopenia (Age-related loss of skeletal muscle mass and strength)
Conditions
Interventions
Intervention 1: Intervention group: Here’s the English translation of your provided text:Based on studies, a combination of whey protein, glutamine, beta-hydroxy-beta-methylbutyrate (HMB), creatine, a
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: Age between 18 and 55 years Body Mass Index (BMI) between 30 and 50 Patients with an ASA Score of PS1 or PS2 Receiving the same dietary regimen
Exclusion criteria
Exclusion criteria: Previous history of bariatric surgery Severe liver dysfunction (based on ultrasound findings or liver enzyme levels: Alanine aminotransferase (ALT) > 50 U/L, Aspartate aminotransferase (AST) > 50 U/L, Alkaline phosphatase (ALP) > 300 U/L) Any renal disease Allergy or intolerance to the supplement Any condition that prevents the patient from continuing the study Lack of willingness to continue participation Use of any new nutritional or pharmaceutical supplements that may interfere with the intervention Non-adherence to supplement intake for more than 20% of the intervention period Non-adherence to the dietary regimen for more than 20% of the intervention period
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skeletal muscle mass(Measuring the amount of muscle changes in the body). Timepoint: Pre-intervention, and 1, 3, and 6 months post-surgery. Method of measurement: Bioimpedance analysis(BIA device: inbody570).;Muscular strength (measurement of changes). Timepoint: Pre-intervention, and 1, 3, and 6 months post-surgery. Method of measurement: handgrip dynamometer.;Muscular function (measurement of changes). Timepoint: Pre-intervention, and 1, 3, and 6 months post-surgery. Method of measurement: In the 4 meter gait speed test, the time required to walk 4 meters is measured. In the 5 times sit to stand test (5STS), the time required to sit and stand up from a chair 5 times in succession. The time taken from the start of the first movement to the end of the last movement is recorded using a stopwatch. | — |
Secondary
| Measure | Time frame |
|---|---|
| Fat mass. Timepoint: Pre-intervention, and 1, 3, and 6 months post-surgery. Method of measurement: Bioimpedance analysis(BIA device: inbody570).;Physical activity. Timepoint: Pre-intervention, and 1, 3, and 6 months post-surgery. Method of measurement: IPAC questionnaire.;Weight loss. Timepoint: Pre-intervention, and 1, 3, and 6 months post-surgery. Method of measurement: Bioimpedance analysis(BIA device: inbody570). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contactprofessor Razieh Khalouifard
Tehran University of Medical Sciences
Outcome results
None listed