The Relationship Between Intraoperative Urine Output and Kidney Function After Orthopedic Surgery

The relationship between intraoperative urine volume and post operative serum creatinine level with and without diuretics in major orthopedic surgeries

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20260104068540N1

Enrollment

140

Registered

2026-01-15

Start date

2026-01-15

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

kidney function. Abnormal results of kidney function studies

Interventions

Intervention 1: Intervention group: The diuretic group. (0.5 mg/kg furosemide IV injection at one minute in last 30 min of surgery). Intervention 2: Control group: Normal saline group (as needed).

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age over 18 years consent to participate in the study Candidates for major orthopedic surgery ASA class 1 or 2

Exclusion criteria

Exclusion criteria: Refusal to participate in the study Patients with liver disorders Patients with kidney disorders Patients with a history of advanced cardiovascular diseases Patients on diuretic medications or with hypersensitivity to diureti

Design outcomes

Primary

Measure	Time frame
Serum creatinine levels before and after surgery. Timepoint: before and after the surgery. Method of measurement: blood test.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactYashar Eslampour

Tabriz University of Medical Sciences

y.eslampoor@gmail.com+98 914 311 1033

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026