Comparison of the effect of bupivacaine and ropivacaine on pain intensity after lumbar fusion surgery

Comparison of the effect of pouring bupivacaine and ropivacaine on the durometer during lumbar fusion surgery on postoperative pain and recovery complications

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20251225068439N1

Enrollment

Registered

2026-04-12

Start date

2026-03-21

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain after lumbar fusion surgery. Other acute postprocedural pain

Interventions

Intervention 1: Intervention Group 1: In lumbar fusion surgery, 8 cc of 0.25% bupivacaine produced by Aburaihan Pharmaceutical Company (4 cc of the drug plus 4 cc of normal saline) is applied once ove

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients 18 to 65 years old Patients undergoing lumbar fusion surgery at 2 or 3 levels American Society of Anesthesiologists (ASA) 1 , 2

Exclusion criteria

Exclusion criteria: addiction Allergy to bupivacaine or ropivacaine or other local anesthetics Previous spinal surgery History of seizure Patient with cardiac arrhythmia

Design outcomes

Primary

Measure	Time frame
Pain intensity. Timepoint: The effect of bupivacaine and ropivacaine on pain intensity in recovery is measured every 10 minutes for 2 hours. Method of measurement: Visual analog scale.;Agitation. Timepoint: The effect of bupivacaine and ropivacaine on the level of agitation in recovery is measured every 10 minutes for 2 hours. Method of measurement: Riker Sedation-Agitation Scale.;Systolic blood pressure. Timepoint: The effects of bupivacaine and ropivacaine on changes in systolic blood pressure are measured every 10 minutes during recovery for a duration of 2 hours. Method of measurement: Digital blood pressure monitor.;Diastolic blood pressure. Timepoint: The effects of bupivacaine and ropivacaine on changes in diastolic blood pressure are measured every 10 minutes during recovery for a duration of 2 hours. Method of measurement: Digital blood pressure monitor.	—

Measure

Time frame

Pain intensity. Timepoint: The effect of bupivacaine and ropivacaine on pain intensity in recovery is measured every 10 minutes for 2 hours. Method of measurement: Visual analog scale.;Agitation. Timepoint: The effect of bupivacaine and ropivacaine on the level of agitation in recovery is measured every 10 minutes for 2 hours. Method of measurement: Riker Sedation-Agitation Scale.;Systolic blood pressure. Timepoint: The effects of bupivacaine and ropivacaine on changes in systolic blood pressure are measured every 10 minutes during recovery for a duration of 2 hours. Method of measurement: Digital blood pressure monitor.;Diastolic blood pressure. Timepoint: The effects of bupivacaine and ropivacaine on changes in diastolic blood pressure are measured every 10 minutes during recovery for a duration of 2 hours. Method of measurement: Digital blood pressure monitor.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr . Mehrdad Masoudifar

Esfahan University of Medical Sciences

Masoudifar@med.mui.ac.ir+98 31 3822 0000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026