The Impact of Shoulder Joint Mobilization in Patients with Idiopathic Frozen Shoulder: A Randomized Clinical Trial

The Impact of Shoulder Mobilization-with-Movement Based on the Mulligan Concept on Inferior Shoulder Capsule Thickness and Motor Cortex Excitability in the Frozen Stage of Idiopathic Frozen Shoulder: A Randomized Clinical Trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20251221068399N1

Enrollment

Registered

2025-12-26

Start date

2026-01-20

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Frozen Shoulder. Adhesive capsulitis of shoulder

Interventions

Intervention 1: Control group: healthy control group. Intervention 2: Intervention group: Intervention Group 1 (Patient Control). Intervention 3: Intervention group: Intervention Group 2.

Eligibility

Sex/Gender

All

Age

40 Years to 60 Years

Inclusion criteria

Inclusion criteria: Being 40–60 years of age; experiencing gradual and progressive shoulder pain over the past 3–6 months; reporting pain at the end ranges of shoulder motion; having a Numeric Pain Rating Scale score between 4 and 6; presenting with a confirmed diagnosis of idiopathic frozen shoulder in the frozen stage; and demonstrating passive external rotation restricted to less than 30 degrees.

Exclusion criteria

Exclusion criteria: The presence of systemic diseases; coexisting musculoskeletal disorders of the shoulder; any contraindications to transcranial magnetic stimulation; a history of physiotherapy or corticosteroid injections within the preceding six months; use of medications known to influence cortical excitability; and consumption of caffeine within 24 hours prior to the assessments.

Design outcomes

Primary

Measure	Time frame
Inferior Glenohumeral Capsule Thickness. Timepoint: Before treatment, immediately after treatment, and two months after treatment. Method of measurement: Ultrasound Imaging.	—

Secondary

Measure	Time frame
Motor Cortex Excitability. Timepoint: Before treatment, immediately after treatment, and two months after treatment. Method of measurement: Transcranial Magnetic Stimulation.;Shoulder Cardinal Range of Motion. Timepoint: Before treatment, immediately after treatment, and two months after treatment. Method of measurement: Goniometer.;Shoulder Functional Performance. Timepoint: Before treatment, immediately after treatment, and two months after treatment. Method of measurement: Shoulder Pain and Disability Index (SPADI questionnaire).	—

Measure

Time frame

Motor Cortex Excitability. Timepoint: Before treatment, immediately after treatment, and two months after treatment. Method of measurement: Transcranial Magnetic Stimulation.;Shoulder Cardinal Range of Motion. Timepoint: Before treatment, immediately after treatment, and two months after treatment. Method of measurement: Goniometer.;Shoulder Functional Performance. Timepoint: Before treatment, immediately after treatment, and two months after treatment. Method of measurement: Shoulder Pain and Disability Index (SPADI questionnaire).

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Khandaloo

Semnan University of Medical Sciences

alikhandaloo1997@gmail.com+98 23 3330 0397

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026