Investigation of the effect of laser on dry mouth

Investigation of the adjuvant effect of low level laser therapy in patients with xerostomiaf

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20251218068374N1

Enrollment

Registered

2026-02-03

Start date

2026-02-04

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Xerostomia. Disturbances of salivary secretion

Interventions

Intervention 1: Intervention group: laser therapy. Intervention 2: Control group: off laser.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Individuals who have dry mouth for any reason.

Exclusion criteria

Exclusion criteria: pregnancy history of epilepsy and seizures presence of precancerous oral lesions

Design outcomes

Primary

Measure	Time frame
Salivary flow. Timepoint: Salivary flow measurements at the beginning of the study (before the intervention) and 10 days after the start of laser therapy. Method of measurement: Unstimulated saliva is used. During the collection of unstimulated saliva, subjects will be asked to sit and minimize mouth movement or swallowing and sucking, and saliva will be collected in the floor of their mouth for 60 seconds. They will then spit it into a pre-weighed tube. This will be done for 5 minutes at a time. The unstimulated saliva flow rate will be recorded in ml/min.;Xerostomia Inventory Questionnaire Score. Timepoint: at the beginning of the study (before the intervention) and 10 days after the start of laser therapy. Method of measurement: Total score of the xerostomia inventory questionnaire.	—

Measure

Time frame

Salivary flow. Timepoint: Salivary flow measurements at the beginning of the study (before the intervention) and 10 days after the start of laser therapy. Method of measurement: Unstimulated saliva is used. During the collection of unstimulated saliva, subjects will be asked to sit and minimize mouth movement or swallowing and sucking, and saliva will be collected in the floor of their mouth for 60 seconds. They will then spit it into a pre-weighed tube. This will be done for 5 minutes at a time. The unstimulated saliva flow rate will be recorded in ml/min.;Xerostomia Inventory Questionnaire Score. Timepoint: at the beginning of the study (before the intervention) and 10 days after the start of laser therapy. Method of measurement: Total score of the xerostomia inventory questionnaire.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactNegin Neshanifard

Tabriz University of Medical Sciences

info@dentistryfac.tbzmed.ac.ir+98 41 3335 5965

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026