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Comparing the effect of testosterone injection with human gonadotropin on the length and width of the penis in boys under 3 years of age with micropenis

Randomized clinical trial comparing the effect of testosterone injection with human gonadotropin on the length and width of the penis in boys under 3 years of age with micropenis

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20251211068288N1
Enrollment
30
Registered
2026-01-10
Start date
2026-02-06
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Micro penis. Disorder of penis, unspecified

Interventions

Intervention 1: Group A: Testosterone enanthate injection 2 mg based on weight every 3 weeks for up to 3 doses based on patient needs (the patient is examined at 3-week intervals and the medication is

Sponsors

Kerman University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
No minimum to 3 Years

Inclusion criteria

Inclusion criteria: Micropenis without comorbidities (all patients with symptoms of micropenis) Age less than 3 years Diagnosis of micropenis based on the criterion of penile length less than 2.5 standard deviations below the mean for age (with karyotype 46,XY). No history of micropenis treatment Written consent from parents/legal guardians to participate in the study

Exclusion criteria

Exclusion criteria: Gender ambiguity History of anaphylactic shock Infants or children with chromosomal abnormalities or karyotypes other than 46,XY (such as Klinefelter syndrome, gonadal dysgenesis, or other disorders of sex differentiation) Presence of severe hypospadias Chronic or severe systemic diseases (such as advanced heart, kidney, or liver disease). History of sensitivity or severe reaction to testosterone or hCG. Presence of other metabolic or endocrine diseases that affect sexual development (such as hypothyroidism or adrenal disorders).

Design outcomes

Primary

MeasureTime frame
Width. Timepoint: At the beginning of the study, 3 weeks later, 3 months later, and after the end of the study (6 months later). Method of measurement: Ruler.;Length. Timepoint: At the beginning of the study, 3 weeks later, 3 months later, and after the end of the study (6 months later). Method of measurement: Ruler.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamed Jabalbarezi

Kerman University of Medical Sciences

Hamed.jabalbarezi@gmail.com+98 34 3222 3655

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026