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The Effect of Interval Training on Women with Obesity

The Effect of a Course of High-Intensity Interval Training on NRG-4, Irisin, Asprosin, and Insulin Resistance in Women with Obesity

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT20251211068287N3
Enrollment
20
Registered
2026-02-11
Start date
2026-02-20
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obese Women. Body mass index (BMI) pediatric, 85th percentile to less than 95th percentile for age

Interventions

Intervention group: High Intensity Interval Training.

Sponsors

Ilam University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Having a sedentary lifestyle (defined by IPAQ criteria) for a minimum of 6 months prior to the study Having a Body Mass Index (BMI) = 30 kg/m² Signing an informed consent form to participate in the study.

Exclusion criteria

Exclusion criteria: Any pre-existing musculoskeletal condition that could limit the ability to perform intense physical training. Use of medications affecting weight, glucose metabolism, or inflammation (such as corticosteroids, anti-obesity drugs, insulin, metformin, etc.) in the past 3 months. History of cardiovascular disease, or uncontrolled hypertension (e.g., systolic blood pressure >140 or diastolic blood pressure >90 mmHg).

Design outcomes

Primary

MeasureTime frame
Neuregulin-4. Timepoint: Before and after the 12-week exercise intervention. Method of measurement: Enzyme-Linked Immunosorbent Assay (ELISA).

Secondary

MeasureTime frame
Irisin. Timepoint: Before and after the 12-week exercise intervention. Method of measurement: Enzyme-Linked Immunosorbent Assay (ELISA).;Asprosin. Timepoint: Before and after the 12-week intervention. Method of measurement: Enzyme-Linked Immunosorbent Assay (ELISA).;Insulin Resistance. Timepoint: Before and after the 12-week intervention. Method of measurement: Enzyme-Linked Immunosorbent Assay (ELISA).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKamran Taherpour

Ilam University

kamran_taherpour@ilam.ac.ir+98 84 5924 1000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026