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Comparison of itching after different doses of fentanyl in patients undergoing lower extremity orthopedic surgery under spinal anesthesia”

Comparison of the Incidence of Pruritus Following Different Doses of Intrathecal Fentanyl in Patients Undergoing Lower Limb Orthopedic Surgery with Spinal Anesthesia: A Randomized Double-Blind Clinical Trial

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
IRCT
Registry ID
IRCT20251209068259N1
Enrollment
150
Registered
2025-12-24
Start date
2025-12-22
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

“Comparison of itching after different doses of fentanyl in patients undergoing lower extremity orthopedic surgery under spinal anesthesia”. Unspecified adverse effect of drug or medicament

Interventions

Intervention 1: Intervention group: Spinal puncture will be performed at the L3–L4 interspace using a 23-gauge needle as follows. Intervention 2: Intervention group: Group B received 15 mg of bupivaca

Sponsors

Jahrom University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients with an American Society of Anesthesiologists (ASA) physical status classification of I–III who are scheduled to undergo lower extremity orthopedic surgery, including hip or knee arthroplasty and fracture surgery, under spinal anesthesia will be considered eligible for inclusion.”

Exclusion criteria

Exclusion criteria: Contraindications to spinal anesthesia include coagulation disorders, schizophrenia, a history of trauma or spinal diseases that make the performance of spinal anesthesia difficult, and infection at the puncture site.

Design outcomes

Primary

MeasureTime frame
The percentage of individuals who experienced itching during the procedure. Timepoint: Upon entering the operating room (before spinal anesthesia), immediately after spinal anesthesia, at 15, 30, 45, 60, 90, and 120 minutes during the operation, upon admission to the recovery room, and upon discharge from the recovery room. Method of measurement: NRS Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactReza Sahrae

Jahrom University of Medical Sciences

sahraeir1354@gmail.com+98 71 5423 0010

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026