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Effectiveness of progesterone suppositories

Comparing the effectiveness of progesterone suppositories and proluton ampoules in preventing preterm labor

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
IRCT
Registry ID
IRCT20251208068247N1
Enrollment
222
Registered
2025-12-23
Start date
2025-12-22
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Premature Birth. Premature/Birth NEC

Interventions

Intervention 1: Intervention group: This group will receive 200 mg of vaginal progesterone suppositories (Abo Raihan Pharmaceutical Company, Tehran, Iran) daily. Intervention 2: Control group: The sec

Sponsors

Ardabil University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Non smoking women Single pregnancy Gestational age 28-34 weeks Age:18-37 years

Exclusion criteria

Exclusion criteria: Presence of active vaginal bleeding or definite signs of placental abruption (premature separation of the placenta) History of sensitivity or allergic reaction to progesterone or ingredients of the study drugs (suppositories or ampoules)

Design outcomes

Primary

MeasureTime frame
Prevention of premature birth. Timepoint: In the progesterone suppository group, women received it daily from weeks 28 to 34 of pregnancy until week 37 of pregnancy. In the proluton ampoule group, women received it weekly from weeks 28 to 34 of pregnancy until week 37 of pregnancy. Method of measurement: By taking a medical history and examination and recording the information in a checklist.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShervin Tabrizian

Ardabil University of Medical Sciences

Submit1article@gmail.com+98 45 3324 8888

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026