Brain Trauma. Diffuse traumatic brain injury
Conditions
Interventions
Intervention 1: Intervention group: The treatment group is the 5% sodium chloride intravenous bolus treatment group, which receives 50 cc twice a day. This 50 cc is given over 15 minutes. If the plasm
Sponsors
Ahvaz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: Patients with severe head trauma (GCS less than 8) admitted to the ICU who have a sodium level less than 125 millimoles per liter Patients older than 20 years of age Patient consent to participate in the study
Exclusion criteria
Exclusion criteria: Patients with Syndrome of inappropriate antidiuretic hormone ADH release History of surgery History of previous brain trauma History of seizures History of glucocorticoid deficiency History of thyroid disease History of pituitary surgery Patients receiving diuretics Patients with heart failure Patients with renal failure
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plasma Sodium. Timepoint: At the start of treatment and then every 4 hours for 48 hours from the initiation of treatment. Method of measurement: Electrolyte Analyzer.;Urine specific gravity. Timepoint: At the start of treatment and then every 4 hours for 48 hours from the initiation of treatment. Method of measurement: Refractometer. | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient's consciousness. Timepoint: During the ICU stay. Method of measurement: Glasgow Coma Scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFereshte Amiri
Ahvaz University of Medical Sciences
Outcome results
None listed