Chronic rhinosinusitis with nasal polyposis.
Conditions
Interventions
Intervention 1: Intervention group: Received hypertonic saline solution combined with budesonide for nasal irrigation. Intervention 2: Intervention group: Received intranasal fluticasone spray.
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Age over 18 years Diagnosis of chronic rhinosinusitis with nasal polyposis based on the criteria of the Rhinology Society Successful completion of Functional Endoscopic Sinus Surgery (FESS) Written informed consent to participate in the study No use of systemic corticosteroid medications within the past 4 weeks
Exclusion criteria
Exclusion criteria: History of allergy or intolerance to the study medications (budesonide or fluticasone Presence of severe underlying diseases such as immunodeficiency, uncontrolled diabetes, or advanced cardiac disease Lack of cooperation in completing questionnaires or attending follow-up visits Occurrence of severe postoperative complications requiring treatment outside the study protocol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity score of sinusitis in the SNOT-22 questionnaire. Timepoint: Before surgery and at the fourth week after surgery. Method of measurement: SNOT-22 questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAli Golmohammadi
Tabriz University of Medical Sciences
Outcome results
None listed