Soft tissue healing condition around dental implants. Disorder of gingiva and edentulous alveolar ridge, unspecified
Conditions
Interventions
Intervention 1: In the intervention group1:L-PRF will be prepared from the patient’s venous blood using standard centrifugation protocols. The obtained membranes will be applied during surgery in the
Sponsors
Rasht University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Age 18–65 years Need for implant placement in anterior esthetic zone Systemically healthy with no chronic conditions affecting healing Good oral hygiene status Signed written informed consent
Exclusion criteria
Exclusion criteria: Uncontrolled diabetes or cardiovascular/systemic diseases affecting healing Coagulopathy or blood disorders Use of anticoagulants or immunosuppressive drugs Severe allergy or hypersensitivity Pregnancy or lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Soft tissue outcome around dental implants including keratinized tissue height, soft tissue thickness, inflammation index and peri-implant mucosal healing profile. Measurements will be compared between CGF/PRF groups. Timepoint: Baseline (pre-surgery), 1 month, 3 months (and 6 months follow-up if available). Method of measurement: Soft tissue thickness and keratinized tissue height measured in millimeters using periodontal probe/digital caliper, clinical indices recorded by direct clinical examination. | — |
Secondary
| Measure | Time frame |
|---|---|
| Keratinization of gingival tissue: measurement of the degree of gingival tissue keratinization. Timepoint: At 1, 2, 4, and 8 weeks and at 3 and 6 months after surgery. Method of measurement: Soft tissue assessment will be performed using a periodontal probe or digital caliper to measure keratinized tissue height and soft tissue thickness in millimeters. Clinical healing and inflammation indicators will be recorded through direct clinical examination at each time point.;Implant radiography: assessment of implant status and evaluation of marginal bone loss. Timepoint: At 3 and 6 months after surgery. Method of measurement: To evaluate marginal bone level changes around the implant, standardized periapical radiographs will be obtained using the paralleling technique and a film/sensor holder to ensure consistent X-ray angulation and sensor positioning at all imaging sessions. Marginal bone loss will be measured in millimeters from the implant platform to the first bone-to-implant contact (fBIC) at the mesial and distal aspects using calibrated digital software. Each measurement will be performed twice and the mean value will be recorded. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Parisa Mohammadi
Rasht University of Medical Sciences
Outcome results
None listed