Effect of combined exercise and gamma oryzanol supplementation on adipokines and diabetes

The effect of combined exercise with Gamma oryzanol supplementation on Asprosin, Apelin levels, insulin resistance, Oxidative stress and body composition in men with type 2 diabetes

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20251205068219N1

Enrollment

Registered

2026-05-05

Start date

2026-05-15

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes. Type 2 diabetes mellitus

Interventions

Intervention 1: Intervention group: exercise group. Intervention 2: Intervention group: supplements gamma oryzanol ? 600 mg daily as two 300 mg capsules taken with breakfast and dinner for 8 weeks.Ga

Eligibility

Sex/Gender

Male

Age

40 Years to 60 Years

Inclusion criteria

Inclusion criteria: All diabetic patients who have had diabetes for more than three years Only use metformin to treat diabetes. HbA1C is above 6.5 Do not smoke.

Exclusion criteria

Exclusion criteria: Have a heart problem Take insulin. Be an athlete

Design outcomes

Primary

Measure	Time frame
Decrease Asprosin. Timepoint: At the beginning of starting to study and after 2 month's. Method of measurement: Elisa kits.	—

Secondary

Measure	Time frame
Reduce oxidative stress. Timepoint: Before starting the study and 2 months later. Method of measurement: Elisa kits.;Reduce inflation. Timepoint: After the start of study and 2 months later. Method of measurement: Elisa kits.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehdi Rostamizadeh

The University of Urmia

m.rostamizadeh@urmia.ac.ir+98 41 4434 0369

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026