Chronic pain in patients with blunt chest trauma. Chronic pain due to trauma
Conditions
Interventions
Intervention 1: Intervention group: patients in this group will receive oral pregabalin, with an initial dose of 25 mg once daily. In addition, patients will receive naproxen 250 mg orally twice daily
Sponsors
Kerman University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Chronic thoracic pain (persistent pain in the thoracic region for at least 12 weeks) following blunt chest trauma Age between 18 and 75 years Failure of previous conservative management, including physical therapy and non-opioid pain medications
Exclusion criteria
Exclusion criteria: History of allergic reactions to pregabalin, NSAIDs, or any of their components Presence of severe renal impairment (estimated glomerular filtration rate less than 30 ml/min). History of bleeding or peptic ulcer in the past six months Current or previous use of pregabalin or gabapentin in the past month Presence of significant psychiatric disorders, including major depression and anxiety disorders, that may interfere with participation in the study Pregnant or breastfeeding women. Patients with a history of substance abuse or current opioid use Patients with a history of epilepsy or any other neurological disorder that may contraindicate the use of pregabalin
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intensity of pain. Timepoint: Patients will attend study visits at baseline, 2 weeks, 4 weeks, 8 weeks, and 12 weeks. Method of measurement: Assessing pain intensity using a Numerical Rating Scale (NRS). | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence and severity of side effects. Timepoint: Patients will attend study visits at baseline, 2 weeks, 4 weeks, 8 weeks, and 12 weeks. Method of measurement: A checklist for recording possible drug side effects, which includes drowsiness, dizziness, abdominal pain, nausea, vomiting, allergic skin reactions, peripheral edema, and blurred vision, is completed at each visit. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactShiva Bahremand
Kerman University of Medical Sciences
Outcome results
None listed