Skip to content

The effect of resistance exercise with and without blood flow restriction during different phases of the menstrual cycle in trained women

Hormonal, Lactate, and Cardiac Autonomic Responses to Resistance Exercise with and Without Blood Flow Restriction at Menstrual Cycle Phases in Trained Women

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20251202068190N1
Enrollment
12
Registered
2026-04-11
Start date
2025-06-17
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Menstrual cycle status.

Interventions

Intervention 1: Control group: Resistance exercise without Blood Flow Restriction
Participants will perform traditional resistance exercise at an intensity of 70% of one-repetition maximum (1RM). The training protocol will include of two exercises, leg press and leg extension, each
Participants in this group will perform resistance exercises (leg press and leg extension) at an intensity of 30% of 1RM. BFR will be applied using a cuff placed at the proximal portion of the lower l

Sponsors

University of Guilan
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 30 Years

Inclusion criteria

Inclusion criteria: Trained women with at least six months of regular resistance training experience Regular menstrual cycles (28–32 days) Range of age between 20 to 30 years

Exclusion criteria

Exclusion criteria: Taking hormonal medications or oral contraceptives during the past six months Consumption of nutritional supplements or caffeine at least 48 hours prior to testing The history of cardiovascular, metabolic, endocrine, or neurological diseases

Design outcomes

Primary

MeasureTime frame
Growth hormone. Timepoint: Pre-test (before the exercise session) and post-test (after the test/end of the exercise session). Method of measurement: Serum growth hormone concentration will be measured through blood sampling and laboratory assessment using the Enzyme-Linked Immunosorbent Assay (ELISA) method.;Cortisol. Timepoint: Pre-test (before the exercise session) and post-test (after the test/end of the exercise session). Method of measurement: Serum cortisol concentration will be measured using blood sampling and laboratory analysis by the enzyme-linked immunosorbent assay (Enzyme-Linked Immunosorbent Assay).;Blood Lactate. Timepoint: Pre-test (before the exercise session) and post-test (after the test/end of the exercise session). Method of measurement: Plasma lactate level will be measured using blood sampling and laboratory analysis by a standard enzymatic method.;Heart Rate Variability. Timepoint: Heart rate variability will be recorded and analyzed in 5-minute time windows during the pre-test period and immediately after the test. Method of measurement: Heart rate variability will be measured and analyzed using a Polar H10 heart rate sensor.

Secondary

MeasureTime frame
Blood Pressure. Timepoint: Pre-test (before the exercise session) and post-test up to 60 minutes after the test. Method of measurement: By using Sphygmomanometer.;Rating of Perceived Exertion (RPE). Timepoint: Immediately after completion of each set of the exercise. Method of measurement: By using the Borg rating of perceived exertion scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Aftabi Talami

University of Guilan

zahraaftabi.t@gmail.com+98 13 3369 0685

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026