Postoperative joint stiffness, distal radius fracture, limitation of wrist range of motion. Stiffness of wrist, not elsewhere classified
Conditions
Interventions
Intervention 1: Intervention group: Intervention Group (HA group): Patients will receive a single 2 mL intra-articular injection of hyaluronic acid (e.g., sodium hyaluronate 20 mg/2 mL) after wound cl
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Adults aged 18 to 70 years Acute, closed distal radius fracture requiring ORIF with volar plate Ability and willingness to provide written informed consent and adhere to the follow-up schedule
Exclusion criteria
Exclusion criteria: Open or pathological fractures Previous surgery or trauma to the affected wrist Systemic inflammatory joint disease (e.g., rheumatoid arthritis) Known allergy to Hyaluronic Acid or its components Local or systemic infection Inability to participate in rehabilitation or follow-up Intraarticular fracture
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Wrist range of motion (flexion–extension), measured using a goniometer by a blinded assessor at 12 weeks post-operation. Timepoint: Wrist flexion–extension ROM will be measured at week 6 and at week 12 after surgery. Method of measurement: Wrist joint range of motion will be measured using a standard goniometer by a trained and blinded assessor. | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain intensity measured using the Visual Analogue Scale by a blinded assessor at weeks two, six, and twelve after surgery. Timepoint: Pain intensity measured at weeks two, six, and twelve after surgery. Method of measurement: Visual Analogue Scale by a blinded assessor.;Wrist functional status measured using the Quick Disabilities of the Arm, Shoulder and Hand questionnaire at weeks six and twelve after surgery. Timepoint: at weeks six and twelve after surgery. Method of measurement: the Quick Disabilities of the Arm, Shoulder and Hand questionnaire at weeks six and twelve after surgery.;Postoperative complications including persistent joint stiffness, joint swelling, and infection assessed up to week twelve after surgery. Timepoint: up to week twelve after surgery. Method of measurement: Postoperative complications including persistent joint stiffness, joint swelling, and infection will be assessed through clinical examination by the treating physician and documented using a standard clinical evaluation checklist. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactIbrahim Alkhuzaie
Tehran University of Medical Sciences
Outcome results
None listed