Evaluation of Saline Injection Embolization at the Biopsy Site for Prevention of Pneumothorax Following Lung Biopsy (A Clinical Trial)

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20251130068157N1

Enrollment

136

Registered

2025-12-14

Start date

2025-12-06

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pneumothorax following lung mass biopsy. Malignant neoplasm of bronchus and lung

Interventions

Intervention 1: Intervention group: :In the saline embolization group, during withdrawal of the coaxial needle, 3 cc of normal saline is injected into the needle tract. The coaxial needle is withdrawn

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Individuals who meet the indications for lung biopsy

Exclusion criteria

Exclusion criteria: The biopsy needle does not traverse aerated lung tissue Bleeding is visible along the needle tract before removal Procedure failure resulting from patient non-cooperation Pneumothorax occurring prior to removal of the coaxial needle Patients who have undergone ultrasound-guided biopsy

Design outcomes

Primary

Measure	Time frame
Pneumothorax. Timepoint: Immediately after the biopsy, at 4 hours, and at 24 hours post-biopsy. Method of measurement: Pneumothorax on CT was defined as the presence of air in the pleural space measuring greater than 1 cm in width.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Hajisafari tafti

Yazd University of Medical Sciences

z.hajisafaritafti@gmail.com+98 35 3183 3803

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026