Study of the Effects of Oral Isotretinoin on Rhinoplasty Results in Patients with Thick Skin referred to 15 Khordad Hospital

Study of the Effects of Oral Isotretinoin on Rhinoplasty Results in Patients with Thick Skin

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20251129068154N1

Enrollment

Registered

2026-01-12

Start date

2026-01-21

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thick nose skin.

Interventions

Intervention 1: "Intervention group": isotertionin consumption 0.3mg/kg from 2 weeks before up to 2 months after rhinoplasty surgery.". Intervention 2: Control group: without any intervention.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age more than 18 Rhinoplasty candidate Thick nose skin due to surgeon opinion

Exclusion criteria

Exclusion criteria: Not permitted by patient Pergnancy and Lactating Metabolic disorders Sensitivity to Isotertinoin Addiction Disobeying patient

Design outcomes

Primary

Measure	Time frame
Skin thickness. Timepoint: 0-1-6 months. Method of measurement: By ultrasound and due to surgeons opinion.	—

Secondary

Measure	Time frame
Hypertrophic scar and kelloid. Timepoint: 0-1-6 months. Method of measurement: Surgeon's visit.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSiavash Vaziri

Shahid Beheshti University of Medical Sciences

cvshvzri@ymail.com9821222911416

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026