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Evaluation of a Mobile-based Neurocognitive Rehabilitation App

Evaluation of a Mobile-based Neurocognitive Rehabilitation App on Executive Functions, Craving and Relapse in Patients under Opioid Maintenance Treatment

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20251121068070N1
Enrollment
120
Registered
2026-02-01
Start date
2026-02-04
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Addiction. Mental and behavioural disorders due to use of opioids

Interventions

Intervention 1: Intervention group: Intervention group: The intervention group worked with the designed cognitive app in 14 sessions (two sessions per week). The app tasks for each session included a

Sponsors

Semnan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: The age range of participants in the study will be 18 to 60 years At least six months have passed since the start of maintenance treatment and he/she is in the maintenance phase. Have been diagnosed with a substance use disorder for at least 12 months based on DSM-5 criteria Must be at least literate and able to complete written and executive tasks of the treatment protocol. Have a mobile phone with Android 4 or higher operating system and be able to work with it. Consent to participate in the research and declare it in writing.

Exclusion criteria

Exclusion criteria: Have schizophrenia or other psychotic disorders. Have acute mental health conditions and problems, such as suicide, etc., that require rapid intervention. Have a positive drug addiction test at the time of pre-test.

Design outcomes

Primary

MeasureTime frame
Working memory score on the Wechsler Working Memory Test. Timepoint: Before the start of the study and 7 weeks after starting to use the app. Method of measurement: Wechsler Working Memory Test.;Cognitive flexibility score from the Dennis and Vander Wal Cognitive Flexibility Questionnaire. Timepoint: Before the start of the study and 7 weeks after starting to use the app. Method of measurement: Dennis and Vander Wal Cognitive Flexibility Questionnaire.;Temptation score from the Post-Quittance Substance Use Temptation Assessment Questionnaire. Timepoint: Before the start of the study and 7 weeks after starting to use the app. Method of measurement: Post-Quittance Substance Use Temptation Assessment Questionnaire.;Response inhibition score in the Stroop color-word test. Timepoint: Before the start of the study and 7 weeks after starting to use the app. Method of measurement: Stroop Color-Word Test.

Secondary

MeasureTime frame
Relapse. Timepoint: Before the intervention and 7 weeks after the first session of using the app. Method of measurement: PRS Return Forecast.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMojtaba Rajabpour

Semnan University of Medical Sciences

mj_rajabpour@yahoo.com+98 23 3344 1022

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026