Atherosclerotic heart disease. Atherosclerotic heart disease of native coronary artery
Conditions
Interventions
Intervention 1: Control group (Fentanyl Alone): After pain assessment 1 hour post-extubation, fentanyl infusion will be initiated at 1–2 µg/kg/h. The dose may be increased to 2–3 µg/kg/h at 4 hours an
Sponsors
Shahid Rajaee Cardiovascular Educational, Research and Treatment Institute
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Age 18–80 years Candidate for non-emergency CABG surgery Willingness to participate in the study Relative consciousness (oriented to time, place, and person) Ability to communicate verbally No history of severe psychiatric disorders (self-reported) Not pregnant No history of drug or alcohol abuse Body weight <100 kg No chronic pain for more than 6 months
Exclusion criteria
Exclusion criteria: Lack of relative consciousness after surgery Postoperative intubation with additional sedatives (e.g., propofol) Withdrawal of consent or non-cooperation Hemodynamic instability Need for cardiopulmonary resuscitation (CPR) Development of postoperative delirium after ketamine administration
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain intensity: Defined as the pain score reported by patients after coronary artery bypass surgery, measured using a visual pain intensity scale. Timepoint: Pain intensity was measured with VAS at 1, 4, 6, 12, and 24 hours after extubation (removal of the breathing tube). Method of measurement: Pain intensity: Assessed using the Visual Analogue Scale (VAS), a 10-cm scale ranging from 0 (no pain) to 10 (worst imaginable pain). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Maryam Ghadimi
Shahid Rajaee Cardiovascular Training, Research and Treatment Center
Outcome results
None listed