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The effectiveness of psychodynamic treatment of depression on the treatment of major depressive disorder and determining the mechanisms of change

The effectiveness of psychodynamic treatment of depression on the treatment of major depressive disorder and determining the mechanisms of change

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20251119068048N1
Enrollment
40
Registered
2025-12-30
Start date
2026-01-21
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Major depressive disorder. Major depressive disorder, single episode

Interventions

Intervention 1: Intervention group: This group will receive psychodynamic therapy for major depressive disorder. Psychodynamic therapy for depression, developed by Frederick Bosch et al. (2004), is a

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Having diagnostic criteria for major depressive disorder based on the Structured Clinical Interview (SCID-5) based on DSM-5 Age range between 18 and 35 years

Exclusion criteria

Exclusion criteria: Receiving psychotherapy from one year before the research was conducted Presence of one or more severe personality disorders (schizoid, schizotypal, paranoid, borderline, and antisocial) using the Structured Clinical Interview for Personality Disorders in DSM-5 Symptoms of psychosis High risk of suicide (assessed using the Beck Suicide Questionnaire) Symptoms of bipolar disorder History of organic brain disorder (based on the contents of the patient's file and questions from the references)

Design outcomes

Primary

MeasureTime frame
Depression score on the Beck Depression Inventory. Timepoint: Before the intervention; After the intervention; Three months after the end of the intervention. Method of measurement: Beck Depression Inventory.

Secondary

MeasureTime frame
Interpersonal problems score. Timepoint: Before the intervention; After the intervention; Three months after the end of the intervention. Method of measurement: Short Form Interpersonal Problems Questionnaire.;Occupational-social adjustment score. Timepoint: Before the intervention; After the intervention; Three months after the end of the intervention. Method of measurement: Work and Social Adjustment Scale (WSAS).;Interpersonal conflict mastery score. Timepoint: Before the intervention; After the intervention; Three months after the end of the intervention. Method of measurement: Grineer Mastery Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaisam Shafiee

Iran University of Medical Sciences

shafiee.m@tak.iums.ac.ir+98 21 4613 4257

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026