The effect of vitamin D in improving anxiety symptoms

Investigating the effect of vitamin D supplementation in improving anxiety symptoms in patients with generalized anxiety disorder over18 years of age

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20251118068035N1

Enrollment

Registered

2025-12-08

Start date

2025-12-22

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Generalized anxiety disorder. Generalized anxiety disorder

Interventions

Intervention 1: Intervention group: Generalized Anxiety Disorder Patients with Normal Vitamin D Levels. Intervention 2: Control group: Generalized Anxiety Disorder Patients with Normal Vitamin D Level

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients aged 18 years and older Definite diagnosis of generalized anxiety disorder Score greater than 15 on the Spitzer Generalized Anxiety Disorder Questionnaire (GAD-7) Serum vitamin D level greater than 30 ng/ml

Exclusion criteria

Exclusion criteria: Pregnancy Breastfeeding Acute physical illness Severe psychiatric disorders (bipolar disorder, schizophrenia)

Design outcomes

Primary

Measure	Time frame
Measuring anxiety levels in patients. Timepoint: Beginning and end of the study. Method of measurement: Spitzer Generalized Anxiety Inventory score.;Measuring vitamin D levels. Timepoint: Beginning and end of the study. Method of measurement: 25 hydroxyVitamin d ????.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Shahmoradi

Arak University of Medical Sciences

Shahmoradizahra@yahoo.com0863819693181

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026