Condition 1: Surgical scar formation site after total thyroidectomy. Condition 2: Postsurgical hematoma after total thyroidectomy. Scar conditions and fibrosis of skin Postprocedural hemorrhage and hematoma of an endocrine system organ or structure following an endocrine system procedure
Conditions
Interventions
Intervention 1: Intervention group: Injection of Injectable Platelet-Rich Fibrin(i-PRF) during the surgery into the surgical bed prior to suturing, and placement of Concentrated Platelet-Rich Fibrin(C
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients who are candidates for total thyroidectomy over 18 years of age No history of neck surgery Normal preoperative calcium levels
Exclusion criteria
Exclusion criteria: Coagulation disorders Use of therapeutic-dose anticoagulant medications(except for prophylaxis) Known sensitivity to any of the components of PRP or fibrin History of radiotherapy or extensive surgery in the neck region Presence of active infection or advanced malignancy with metastasis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postsurgical scar appearance following total thyroidectomy surgery. Timepoint: Immediately after surgery and 1,6 months after surgery. Method of measurement: The Patient and Observer Scar Assessment Scale , The Vancouver Scar Scale.;Patient satisfaction with scar appearance following total thyroidectomy surgery. Timepoint: Immediately after surgery and 1,6 months after surgery. Method of measurement: Visual Analog Scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative drainage duration. Timepoint: during recovery time. Method of measurement: Based on observation of the surgical site.;Postoperative drainage volume. Timepoint: during recovery time. Method of measurement: Based on observation of the surgical site.;Blood calcium level. Timepoint: Before surgery, 1,2 ,7 days after surgery and 1 month after surgery. Method of measurement: Free blood calcium level measured by lab.;Duration of Postoperative Hospitalization. Timepoint: At discharge. Method of measurement: Based on hospitalization documents. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMaryam Namjoo Moghadam
Tehran University of Medical Sciences
Outcome results
None listed