Investigating the effect of isoflavin supplementation and circuit resistance training on the prevention of osteoporosis in military personnel over 40 years of age.

Investigating the effect of isoflavin supplementation and circuit resistance training on the plasma levels of osteoporosis indexes in military personnel over 40 years old

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

IRCT

Registry ID

IRCT20251117068023N1

Enrollment

Registered

2026-01-21

Start date

2026-02-20

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

This study would be implemented on the healthy subjects.

Interventions

Intervention 1: Intervention group: Circuit resistance training + placebo. Intervention 2: Intervention group: Isoflavones supplement. Intervention 3: Intervention group: Circuit resistance training +

Eligibility

Sex/Gender

Male

Age

40 Years to 50 Years

Inclusion criteria

Inclusion criteria: Mission experience in the organization for at least 10 years No smoking No previous cardiovascular, blood, liver, kidney or respiratory diseases At least 40 years of age No use of androgenic and ergogenic supplements for at least 3 months before the tes

Exclusion criteria

Exclusion criteria: Outfit the prerequisitive age range of 40 to 50 years old Adding drug treatments that interfere with the hormonal profile or performance of volunteers Subjects' absence Irregular participation in training programs

Design outcomes

Primary

Measure	Time frame
Plasma levels of Osteoprotegerin. Timepoint: Before and 48 hours subsequent to the training session/supplementation. Method of measurement: Elisa technique.;Plasma levels of receptor activator of nuclear factor kappa-?. Timepoint: Before and 48 hours subsequent to the training session/supplementation. Method of measurement: Elisa technique.;Plasma levels of receptor activator of nuclear factor kappa-? ligand. Timepoint: Before and 48 hours subsequent to the training session/supplementation. Method of measurement: Elisa technique.;Bone mass density. Timepoint: Before and 48 hours subsequent to the training session/supplementation. Method of measurement: Dual-energy X-ray absorptiometry (DEXA).	—

Measure

Time frame

Plasma levels of Osteoprotegerin. Timepoint: Before and 48 hours subsequent to the training session/supplementation. Method of measurement: Elisa technique.;Plasma levels of receptor activator of nuclear factor kappa-?. Timepoint: Before and 48 hours subsequent to the training session/supplementation. Method of measurement: Elisa technique.;Plasma levels of receptor activator of nuclear factor kappa-? ligand. Timepoint: Before and 48 hours subsequent to the training session/supplementation. Method of measurement: Elisa technique.;Bone mass density. Timepoint: Before and 48 hours subsequent to the training session/supplementation. Method of measurement: Dual-energy X-ray absorptiometry (DEXA).

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmir Maleki

Artesh University of Medical Sciences

Maleki6672@yahoo.com+98 21 8609 6350

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026