Study and comparison of pain levels after root canal treatment with two different methods in mandibular molars

Comparison of the effect of Denco and Denflex rotary files on pain after root canal treatment of mandibular first molars with asymptomatic irreversible pulpitis: A randomized clinical trial study

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20251115067998N1

Enrollment

Registered

2025-12-31

Start date

2026-01-21

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asymptomatic irreversible pulpitis in mandibular first molars. Pulpitis

Interventions

Intervention 1: Intervention group 1: In this group, Denco (Super files iii) are used. This file will be used in a clockwise rotary motion passively and with the crown-down technique according to the

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age 20-60 years Mandibular first molars with closed apex and irreversible asymptomatic pulpitis and normal periapical Teeth without radiolucency on radiographs Patient with no history of pain or analgesic use Restorable teeth Teeth capable of root canal treatment in one session

Exclusion criteria

Exclusion criteria: Internal or external resorption in radiography Pulp necrosis PDL widening sinus tract Periapical abscess calcified canal severe canal curvature pain or tenderness Pregnancy Breastfeeding Teeth with periodontal pocket depth greater than 3 mm Underlying systemic disease (blood pressure, gastrointestinal disease, etc.) Teeth that require more than one treatment session and the use of intra-canal medications due to the failure of the canal to dry due to bleeding Allergy Psychological illness Patient with oral habits of bruxism and teeth grinding. Patient with TMJ joint disorders Teeth with extensive crown destruction that require crown lengthening (CL) treatment after root canal therapy Teeth with previous root canal treatment Teeth with a history of trauma Taking more than 400 mg of ibuprofen after treatment.

Design outcomes

Primary

Measure	Time frame
Pain intensity after root canal treatment. Timepoint: At 6, 12, 24, 72 hours after root canal treatment. Method of measurement: The Visual Analog Scale will be used to assess the pain level after treatment. The Visual Analog Scale is a 10 cm long horizontal straight line with numerical values ??arranged at specific intervals. Participants will be asked to assign a score to their pain level. The presence or absence of pain is classified into four groups: no pain (0), mild pain (1-3), moderate pain (4-6), and severe pain (7-10).	—

Measure

Time frame

Pain intensity after root canal treatment. Timepoint: At 6, 12, 24, 72 hours after root canal treatment. Method of measurement: The Visual Analog Scale will be used to assess the pain level after treatment. The Visual Analog Scale is a 10 cm long horizontal straight line with numerical values ??arranged at specific intervals. Participants will be asked to assign a score to their pain level. The presence or absence of pain is classified into four groups: no pain (0), mild pain (1-3), moderate pain (4-6), and severe pain (7-10).

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactFateme Abolhasani Moghadam

Birjand University of Medical Sciences

fatemehabolhasanimoghadam79@gmail.com+98 56 3238 1700

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026