Comparison of the effect of antibiotic therapy and non consumption of antibiotic in the prophylaxis of infection after chemotherapy in children with hematologic malignancies

Comparison of the effect of antibiotic therapy and non consumption of antibiotic in the prophylaxis of infection after chemotherapy in children with hematologic malignancies hospitalized

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20251112067962N1

Enrollment

148

Registered

2025-12-05

Start date

2026-02-20

Completion date

Unknown

Last updated

2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ACUTE LYMPHOBLASTIC LEUKEMIA - acute myeloblastic leukemia.

Interventions

Intervention 1: Intervention group: Intervention Group: The intervention group will be divided into two subgroups: the first subgroup will receive ciprofloxacin at a dose of 20 mg/kg/day (maximum 750

Eligibility

Sex/Gender

All

Age

3 Months to 18 Years

Inclusion criteria

Inclusion criteria: children with hematologic malignancies

Exclusion criteria

Exclusion criteria: allergy to cyprofloxacin or co amoxiclav malignancies other than hematologic like wilms tumor

Design outcomes

Primary

Measure	Time frame
Neutropenic fever. Timepoint: every 2 hours. Method of measurement: Using a digital forehead thermometer.	—

Secondary

Measure	Time frame
Bacterial or viral infection. Timepoint: daily. Method of measurement: blood culture.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDaryoush Ghanbari

Oroumia University of Medical Sciences

dr.daryoush.ghanbari@gmail.com+98 44 4522 2829

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026