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Intradermal Platelet-Rich Plasma (PRP) for treatment Macular Amyloidosis.

Intradermal Platelet-Rich Plasma (PRP) for treatment Macular Amyloidosis.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20251110067952N1
Enrollment
34
Registered
2025-11-14
Start date
2026-01-10
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Macular Amyloidosis. Amyloidosis of skin (E85.-†)

Interventions

Intervention group: Patients diagnosed with macular amyloidosis by a dermatologist and fulfilling the study’s inclusion criteria were enrolled.

Sponsors

Shahed University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Diagnosis of macular amyloidosis by a dermatologist. Normal results for CBC, TSH, BUN, and Creatinine tests.

Exclusion criteria

Exclusion criteria: Having autoimmune diseases Presence of immunodeficiency disorders, including HIV infection Pregnancy Breastfeeding Hypothyroidism Elevated liver enzymes Elevated creatinine levels

Design outcomes

Primary

MeasureTime frame
Prp treatment. Timepoint: From the beginning of the injection procedure to the fifth month(follow-up). Method of measurement: Recording was performed based on the number of injection sessions according to the patients medical record.;Severity of skin Lesions. Timepoint: All treatment sesions. Method of measurement: Clinical assessment was conducted using the Visual Analogue Scale(VAS) and visual inspection of photo graphs at each treatment session.;History of skin disease. Timepoint: prior to study enrollment. Method of measurement: Patient interviews or review of medical records prior to study enrollment.;Gender. Timepoint: Before enrollment. Method of measurement: Demographic form completed before the start of the study.

Secondary

MeasureTime frame
Patient satisfaction regarding the treatment. Timepoint: post treatment. Method of measurement: A five-point questionnaire was conducted three months post-treatment.;Possible complications. Timepoint: each session. Method of measurement: Clinical evaluation was performed at each session, and patient complaints were recorded.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZohreh Khodashenas

Shahed University

z.khodashenas@shahed.ac.ir+98 21 8896 6130

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026