bipolar disorder with ocd. Bipolar disorder
Conditions
Interventions
Intervention 1: Intervention group:Bipolar patients with comorbid obsessive-compulsive disorder are under mood stabilizer treatment, who are not in the acute phase of mood at the beginning of the stud
Sponsors
Ahvaz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Outpatients aged 18 to 60 years with a final diagnosis of bipolar disorder with obsessive-compulsive disorder receiving mood stabilizer or antipsychotic treatment who have taken an SSRI trial for at least 12 weeks and have not responded to treatment People with a Yale-Brown test score above 15 Individuals who have the patient's or guardian's consent to participate in a research project
Exclusion criteria
Exclusion criteria: Presence of a comorbid psychiatric disorder (schizophrenia, post-traumatic stress disorder, depression, eating disorder) Drug or alcohol use in the past 12 months based on history as well as positive drug test at baseline Taking drugs from the pregabalin family such as gabapentin, tiagabine, and topiramate Patient with mental retardation or other neurological cognitive disorders such as dementia, delirium, head trauma, seizures, apnea, obstructive sleep apnea Received ECT in the past 6 months If serious complications occur, the patient will be excluded from the study. Hypersensitivity to pregabalin or any of the ingredients in the placebo Pregnant and lactating women If the patient has a good response to conventional treatments, he/she will not be included in the study In case of impaired kidney function and increased creatinine, the trial should be discontinued
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ?Obsessive-compulsive symptoms?. Timepoint: Weeks 2, 4, 8, and 12?. Method of measurement: ?Yale-Brown Obsessive Compulsive Scale?. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contactshahin norozi
Ahvaz University of Medical Sciences
Outcome results
None listed