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The effect of nanocurcumin gel on mandibular fractures

The effect of nanocurcumin gel on bone healing in patients with bilateral mandibular fractures.

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT20251110067938N1
Enrollment
40
Registered
2026-04-22
Start date
2026-04-09
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bilateral mandibular fracture. Fracture of mandible

Interventions

Intervention group: One side of the fractured mandible will be covered with nanocurcumin gel..

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients with bilateral mandibular fractures where both sides of the fracture have indications for open fracture treatment. Absence of infection and no history of systemic disease that would affect bone healing. Consent to participate in the study

Exclusion criteria

Exclusion criteria: Patients who do not have indications for open treatment of mandibular fractures.

Design outcomes

Primary

MeasureTime frame
Bone healing rate based on radiographic density criteria. Timepoint: Day of surgery, 30 days after surgery, and three months after fracture healing. Method of measurement: Bone density at the fracture site will be assessed by measuring the gray level of pixels in radiographic images, and the fracture density on the side where nanocurcumin was applied will be compared to the opposite side (without the substance).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRoya Barzgar

Tabriz University of Medical Sciences

Royabarzgar7482@gmail.com+98 56 3272 8788

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026