nebulized ketamine for pain management

Efficacy of postoperative nebulized ketamine for pain management after tonsillectomy in children: a randomized controlled trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20251109067931N1

Enrollment

Registered

2026-01-24

Start date

2026-01-20

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post operative pain. Other acute postprocedural pain

Interventions

Intervention group: nebulized ketamine (1 mg/kg, max 50 mg) administered via jet nebulizer 15 minutes in the post-anesthesia care unit (PACU).

Eligibility

Sex/Gender

All

Age

5 Years to 12 Years

Inclusion criteria

Inclusion criteria: Children aged 5-12 years scheduled for elective tonsillectomy ASA I-II

Exclusion criteria

Exclusion criteria: ketamine allergy psychiatric/neurological disorders chronic pain syndromes severe asthma recent respiratory infections Emergency surgery recent opioid use

Design outcomes

Primary

Measure	Time frame
Numeric rating scale (NRS) pain score. Timepoint: Pain is assessed at baseline, 15, 30, 60, 90, 120 minutes, and 4, 8, 12, 24, and 48 hours post-operatively. Method of measurement: Numeric rating scale (NRS).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohsen Arian Nik

Shahid Beheshti University of Medical Sciences

dr.ariannik@gmail.com+98 21 2303 1290

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026