Thyroid nodules. Benign neoplasm of thyroid gland
Conditions
Interventions
Intervention 1: Intervention group: In addition to standard treatment, one 200 microgram selenium capsule from Daru Salamat Pharmed Pharmaceutical Company daily for 4 months. Intervention 2: Control
Sponsors
Ghoum University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Adult patients 18 to 70 years old Diagnosis of thyroid nodules (benign or with indeterminate cytology) Thyroid nodule =1 cm on ultrasound Normal or slightly elevated TSH levels (0.4-4.5 mIU/L) Not taking medications that affect the thyroid (levothyroxine, methimazole, etc.) in the past 3 months
Exclusion criteria
Exclusion criteria: History of thyroid cancer or malignancy on biopsy, evere acute or chronic diseases (liver/kidney failure, advanced autoimmune diseases, heart, lung) use of selenium supplements or antioxidants in the past 3 months pregnancy or breastfeeding sensitivity to selenium supplements or compounds containing it
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in nodule size. Timepoint: At the beginning of the study and 4 months after starting selenium intake. Method of measurement: Ultrasound. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHassan Karimi Yazdi
Ghoum University of Medical Sciences
Outcome results
None listed